John Starr

John Starr

 

 

 

 

Honorary Professor John M Starr

publications

 

 

 

Position

      

Honoray Professor of Health & Ageing
Director, Alzheimer Scotland Dementia Research Centre
Co-Director, Centre for Cognitive Ageing and Cognitive Epidemiology

Co-Director, Scottish Dementia Clinical Research Network
Consultant Physician, NHS Lothian
 

Qualifications

FRCP(Ed)

Email

jstarr@staffmail.ed.ac.uk

Phone

0131 650 4340 or 0131 465 9101

Address

Alzheimer Scotland Dementia Research Centre, 7 George Square, Edinburgh, UK. EH8 9JZ

 

Biography

Having graduated from Cambridge and London, John Starr came to Edinburgh as a research fellow in the Department of Psychiatry in 1989 to investigate the relationship between blood pressure and cognition. After moving to become a research fellow in the Department of Medicine, he spent two years at the Hammersmith Hospital, London before returning as consultant and part-time Senior Lecturer in Geriatric Medicine based at the Royal Victoria Hospital, Edinburgh.

Working with his colleagues Ian Deary and Lawrence Whalley, he has developed his interest in the relationship between physical and mental health. Their work was recognised by their receipt of the Tenovus Scotland Margaret MacLellan Award 2006 for research on 'The Brain including both neurological and psychiatric disorders'. Between 2003-2005, John Starr held a ‘Leading Practice Through Research’ award from the Health Foundation to improve the health assessment of older people with learning disabilities and his clinical duties and national training roles have also moved along this new direction.

John Starr is married to Claire and they have four children. As a member of the William Morris Society he continues his interest begun when he read History of Art, an experience that inspired him to working across traditional disciplinary divides.

 

Professional Membership

Fellow of the Royal Institute of Public Health

Member of the Association of Physicians of Great Britain & Ireland

 

Broad Areas of interest:

 

Research

 

 

 


C
ognitive Ageing

 

Dementia

Intellectual Disability
 

 

Clinical

 

Dementia

Older adults with an Intellectual Disability

Adults with profound and multiple learning disabilities
 

 

Teaching

 

Responsible for Life Cycle theme within MBChB curriculum

 

Highlights of previous research

My main research interests have been in the relationship between physical and mental health. I have also had some interest in C. difficile prevention.
 

Hobbies & interests

Executive member of Alzheimer Scotland
Trustee of Faith in Older People, Scotland

Member of:
William Morris Society
The International Organization for Septuagint and Cognate Studies

 

Other information

Academic Representative on Geriatric Medicine Specialty Advisory Committee

Member of the BGS Education & Training Committee

Director of the Scottish Dementia Clinical Research Network

Co-Director of the Centre for Cognitive Ageing & Cognitive Epidemiology (website http://129.215.112.134/ccace/)

 

Ongoing research projects

 

 

A Randomised Controlled Trial of Continuous Positive Airway Pressure Treatment in Older People with Obstructive Sleep Apnoea Hypopnoea Syndrome (PREDICT)

With Dr Mary Morrell, Dr Renata Riha, Dr Robert Davies, Professor Andrew Nunn, Professor Mark Sculpher, Dr Susan Griffin, Professor John Stradling, Professor Neil Douglas, Dt Anita Simonds & Dr Mark Elliott

Funded by NIHR (HTA)

Study now closed and analysis ongoing.

 

Lothian Birth Cohort 1921 Wave 5

With Professor Ian Deary & Dr Tom Booth

Funded by MRC

This is the fifth wave of a longitudinal study of people born in 1921 with age 11 IQ data. Participants previously seen at ages 79, 83, 87 & 90.

Commencing shortly.

 

Lothian Birth Cohort 1936 Wave 3

With Professor Ian Deary & Professor Joanna Wardlaw

Funded by Age UK

This is the third wave of a longitudinal study of people born in 1936 with age 11 IQ data. Participants previously seen at ages 70 and 73. A further wave is planned at age 79.

 

Lifelong health and wellbeing of the 6-Day Sample of the Scottish Survey 1947

With Professor IJ Deary, Professor A MacLullich, Professor L Paterson, Professor D Batty, Professor J Elliot & Dr C Dibben

Funded by Joint UK Research Councils (LLHWB)

This is a study of people born on the first day of alternate months of 1936 with age 11 IQ data and detailed follow up to age 27.

 

Towards onset prevention of cognition decline in adults with Down syndrome (the TOP-COG study)

With Professor S-A Cooper, Professor M Caslake, Professor J Evans, Dr A Hassiotis, Professor A Holland, Professor A Jahoda, Dr A McConnachie, Professor J Morrison, Dr H Ring & Professor F Sullivan

CSO funded

This is a feasibility RCT of simvastatin in adults with Down syndrome to prevent dementia/cognitive decline.

 

 

Other projects:

I currently supervise the following PhD students:

Alixe Kilgour (clinical research fellow) – muscle size and its brain structure/function correlates

Tom Russ (clinical research fellow) – spatial clustering of dementia in Scotland

Amanda Barugh (clinical research fellow) – glucocorticoids and stroke

Lewis Killin – short term memory binding in dementia

Ratko Radakovic – apathy in dementia and MND

Anna Lloyd – qualitative longitudinal study of frailty

Aja Murray – the selection problem

Sarah McGrory – item response theory for scales used  in people with dementia

photo of John Starr
Staff Page


Research Links:

**Hospital Acquired Infection**
BMJ Editorial 6th April 2007


HPA Press release
HPA Clostridium difficile data (Excel file)
HPA MRSA data (Excel file)
HPA Clostridium difficile analysis - SPSS output

 

John Starr 2


 

*John receives prestigious award for carrying out the best research on the brain in recent years in Scotland. find out more

John (right) with colleague Ian Deary

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Staff Page

Assessing health status in older adults with Learning Disability

Lothian Birth Cohort 1921 Study

Cognitive function & the ageing brain

 

Publications (2008 onwards):

Seymour DG, Starr JM, Fox H, Lemmon HA, Deary IJ, Prescott G, Whalley LJ. Quality of Life and its Correlates in Octogenarians: Use of the SEIQoL-DW in Wave 5 of the Aberdeen Birth Cohort study (ABC1921). Quality of Life Research 2008;17:11-20. [110]

Starr JM, Pattie A, Whalley LJ, Deary IJ. Predictors of tooth loss in the 1921 Lothian Birth Cohort. Age & Ageing 2008;37:111-114.

Whalley LJ, Deary IJ, Starr JM, Wahle KW, Rance KA, Bourne VJ, Fox HC. n3 fatty acid erythrocyte membrane content, APOE ε4 and cognitive variation: an observational follow-up study in late adulthood. American Journal of Clinical Nutrition 2008;87:449-454.

Starr JM, Lonie J. Estimated pre-morbid IQ effects on cognitive and functional outcomes in Alzheimer disease: a longitudinal study in a treated cohort. BMC Psychiatry 2008;8:27

Johnson W, Harris SE, Starr JM, Whalley LJ, Deary IJ. PPARG Pro12Ala Genotype and Risk of Cognitive Decline in Elders? Maybe in the Presence of Diabetes. Neuroscience Letters 2008;434:50-55.

Starr JM, Marsden L. Characterisation of User-defined Health Status in Older Adults with Intellectual Disabilities. Journal of Intellectual Disability Research 2008;52:483-489.

Sanchez-Hurtado K, Corretge M, Mutlu E, McIlhagger R, Starr JM, Poxton IR. The systemic antibody response to Clostridium difficile in colonised patients with and without symptoms and matched controls. Journal of Medical Microbiology 2008;57:717-724.

Waiter G, Fox H, Murray A, Starr J, Staff R, Bourne V, Whalley L, Deary I. Is retaining the youthful functional anatomy underlying speed of information processing a signature of successful cognitive ageing?: an event-related fMRI study of inspection time performance. Neuroimage 2008;41:581-595.

Luciano M, Lind PA, Deary IJ, Payton A, Posthuma D, Butcher LM, Bochdanovits Z, Whalley LJ, Visscher PM, Harris SE, Polderman TJC, Davis OSP, Wright MJ, Starr JM, de Geus EJC, Bates TC, Montgomery GW, Boomsma DI, Martin NG, Plomin R. Testing replication of a 5-SNP set for general cognitive ability in six population samples. European Journal of Human Genetics 2008;16:1388–1395.

Tenesa A, Farrington SM, Prendergast JGD, Porteous ME, Walker M, Haq N, Barnetson RA, Theodoratou E, Cetnarskyj R, Cartwright N, Wilson R, Semple C, Clarke AJ, Reid FJL, Smith LA, Kavoussanakis K, Kossler T, Pharoah PDP, Buch S, Schafmayer C, Tepel J, Schreiber S, Völzke H, Schmidt CO, Hampe J, Wilkening S, Canzian F, Chang-Claude J, Hoffmeister M, Brenner H, Capella G, Moreno V, Deary IJ, Starr JM, Tomlinson IPM, Webb E,  Houlston RS, Rennert G, Ballinger D, Rozek L, Gruber SB, Matsuda K, Kidokoro T, Nakamura Y, Zanke BW, Greenwood CMT, Rangrej J, Kustra R, Montpetit A, Hudson TJ, Gallinger S, Campbell H, Dunlop MG. A genome-wide association scan identifies three colorectal cancer susceptibility loci. Nature Genetics 2008;40:631-637.

Starr JM, Fox H, Harris SE, Deary IJ, Whalley LJ. GSTZ1 genotype and cognitive ability. Psychiatric Genetics 2008;18:211-212.

Starr JM, Deary IJ, Whalley LJ. All-cause mortality in the Aberdeen 1921 birth cohort: Effects of socio-demographic, physical and cognitive factors. BMC Public Health 2008; 8: 307.

McGurn B, Deary IJ, Starr JM. Childhood cognitive ability and risk of late-onset Alzheimer and Vascular dementia. Neurology 2008;71:1051-1056.

Starr JM, Hall RJ, Macintyre S, Deary IJ, Whalley LJ. Predictors and correlates of edentulism in
the Healthy Old People in Edinburgh (HOPE) study. Gerodontology 2008;25:199-204.

Shenkin SD, Starr JM, Dunn JM, Carter S, Deary IJ. Is there information contained within the sentence-writing component of the Mini Mental State Examination? A retrospective study of community dwelling older people. International Journal of Geriatric Psychiatry2008;23:1283-1289.

Starr JM, Shiels PG, Harris SE, Pattie A, Pearce MS, Relton CL, Deary IJ. Oxidative stress, telomere length and biomarkers of physical aging in a cohort aged 79 years from the 1932 Scottish Mental Survey. Mechanisms of Ageing and Development 2008;129:745-751.

Gow AJ, Johnson W, Pattie A, Whiteman MC, Whalley L, Starr J, Deary IJ. Mental ability in childhood and cognitive aging. Gerontology 2008;54:177-186.

Starr JM, Campbell A, Renshaw E, Poxton IR, Gibson GJ. Spatio-temporal stochastic modelling of Clostridium difficile. Journal of Hospital Infection 2009;71:49-56.

Bochdanovits Z, Gosso  FM, van den Berg  L, Rizzu  P, Polderman  TJC, Pardo LM, Houlihan LM, Luciano M, Starr JM, Harris SE, Deary IJ, de Geus EJC, Boomsma  DI, Heutink  P, Posthuma  D. A functional polymorphism under positive evolutionary selection in ADRB2 is associated with human intelligence with opposite effects in the young and the elderly. Behavior Genetics 2009;39:15-23.

Luciano M, Miyajima F, Lind PA, Bates TC, Horan M, Harris SE, Wright MJ, Hayward C, Ollier W, Pendleton  N, Gow AJ, Visscher PM, Starr JM, Deary IJ, Martin NG, Payton A. Variation in the Dysbindin gene and normal cognitive function in three independent population samples. Genes, Brain and Behavior 2009;8:218-227.

Luciano M, Gow A, Taylor MD, Hayward C, Harris SE, Campbell H, Porteous DJ, Starr JM, Visscher PM, Deary IJ. Apolipoprotein E is not related to memory abilities at 70 years of age. Behavior Genetics 2009;39:6-14.

Deary IJ, Waiter G, Staff R, Murray A, Fox HC, Starr JM, Whalley LJ. Exploring possible neural mechanisms of intelligence differences using processing speed and working memory tasks: an fMRI study. Intelligence 2009;37:199-206.

Starr JM, Farrall AJ, Armitage P, McGurn B, Wardlaw J. Blood-brain barrier permeability in Alzheimer’s disease: a case-control MRI study. Psychiatry Research Neuroimaging 2009;171:232-241.

Luciano M, Gow AJ, Harris SE, Hayward C, Allerhand M, Starr JM, Visscher PM, Deary IJ. Cognitive Ability at Age 11 and 70 Years, Information Processing Speed, and APOE Variation: The Lothian Birth Cohort 1936 Study. Psychology and Aging 2009;24:129-138.

Shenkin SD, Bastin ME, MacGillivray TJ, Deary IJ, Starr JM, Wardlaw JM. Birth parameters are associated with late life white matter integrity in community-dwelling older people. Stroke 2009;40:1225-1228.

Shenkin SD, Rivers CS, Deary IJ, Starr JM, Wardlaw JM. Maximum (prior) brain size, not atrophy, correlates with cognition in community-dwelling older people: a cross-sectional neuroimaging study. BMC Geriatrics 2009;9,12.

Brown LJE, McGrory S, McLaren L, Starr JM, Deary IJ, MacLullich AMJ. Visual Perceptual Deficits in Delirium. Journal of Neurology, Neurosurgery, and Psychiatry 2009;80:594-599.

Luciano M, Marioni RE, Gow AJ, Starr JM, Deary IJ. Reverse causation in the association between C Reactive Protein and fibrinogen levels and cognitive abilities in an aging sample. Psychosomatic Medicine 2009;71:404-409.

Bates TC, Price JF, Harris SE, Marioni RE, Fowkes FG, Stewart MC, Murray GD, Whalley LJ, Starr JM, Deary IJ. Association of KIBRA and memory. Neuroscience Letters 2009;33:14-143.

Shenkin SD, Deary IJ, Starr JM. Birth parameters and cognitive ability in older age: A follow-up study of people born 1921-26. Gerontology 2009;55:92-98.

Houlihan L, Harris SE, Luciano M, Gow AJ, Starr JM, Visscher PM, Deary IJ. Replication study of candidate genes for cognitive abilities: the Lothian Birth Cohort 1936. Genes, Brain and Behavior 2009;8:238-247.

Le Hellard S, Håvik B, Espeseth T, Soule J, Breilid H, Løvlie R, Luciano M, Gow AJ, Harris SE, Starr JM, Wibrand K, Lundervold AJ, Porteous DJ, Bramham CR, Deary IJ, Reinvang I, Steen VM. Variants in doublecortin- and calmodulin kinase like 1, a gene up-regulated by BDNF, are associated with memory and general cognitive abilities. PLoS ONE 2009;4:e7534.

MacLullich AMJ, Ferguson KJ, Reid LM, Deary IJ, Starr JM, Seckl JR, Bastin ME, Wardlaw JM. Higher systolic blood pressure is associated with increased water diffusivity in normal-appearing white matter. Stroke 2009;40:3869-3871.

Penke L, Bates TC, Gow A, Pattie A, Starr JM, Jones BC, Perrett DI, Deary IJ. Symmetric faces are a sign of successful cognitive aging. Evolution and Human Behavior 2009;30:429-437.

Knight H, Pickard B, Maclean A, Malloy M, Soares D, McRae A, Condie A, White A, Hawkins W, McGhee A, van Beck M, Macintyre D, Starr J, Deary I, Visscher P, Porteous D, Cannon R, St Clair D, Muir W, Blackwood D. A cytogenetic abnormality and rare coding variants identify ABCA13 as a candidate gene in schizophrenia, bipolar disorder and depression. American Journal of Human Genetics 2009;85:833-846.

Der G, Allerhand M, Starr JM, Hofer SM, Deary IJ. Age related changes in memory and fluid reasoning in a sample of healthy old people. Aging, Neuropsychology and Cognition 2010;17:55-70.

Starr JM, Kilgour A, Pattie A, Gow A, Bates TC, Deary IJ. Height and intelligence in the Lothian Birth Cohort 1921: a longitudinal study. Age & Ageing 2010;39:272-275.

Corley J, Jia X, Kyle JAM, Gow AJ, Brett C, Starr JM, McNeill G, Deary IJ. Caffeine consumption and cognitive function at age 70: the Lothian Birth Cohort 1936 study. Psychosomatic Medicine 2010;72:206-214.

Harris SE, Hennah W, Thomson PA, Luciano M, Starr JM, Porteous DJ, Deary IJ. Variation in DISC1 is associated with anxiety, depression and emotional stability in elderly women. Molecular Psychiatry 2010;15:232-234.

Deary IJ, Johnson W, Starr JM. Are processing speed tasks biomarkers of cognitive aging? Psychology and Aging 2010;25:219-228.

Nalls MA, Biffi A, Matarin M, Anderson CD, Chasman DI, Bevan S, Spencer CCA, Gschwendtner A, Sale MM, Wu L, Saleheen D, Deary IJ, Langefeld C, Peddareddygari LR, Cole JW, Arapelli SK, Aucutt-Walter N, Brott TG, Broderick JP, Brown DL,  Brown M, Brown RD, Buring JE, Cortellini C, Danesh J, Deka R, Elias GA, Ferrucci L,  Frossard P, Furie K, Gibbs JR, Greenberg SM, Gul M, Hardy J, Harris SE, Hernandez DG, Hsu F-C, Indugula S, Jackson C, Kissela B, Liu L, Metter EJ, Mitchell BD, Murphy L, Mychaleckyj JC, O'Connell JR, Paré G, Parker AN, Patel RK, Poole D, Rasheed A, Richie A, Rothwell PM, Rose L, Ross OA, Rost NS, Schwab K, Sen S, Silliman SL, Soto-Ortolaza AI, Starr JM, Stine OC, Stamova B, Xu H, Wichmann HE, Young LE, Young W, Zaidi M, Zhang H, Kittner SJ, Grewal RP, Woo D, Sudlow C, Kamal AK, Wang X, Sharp FR, Worrall BB, Dichgans M,
Markus HS, Ridker PM, de Bakker PIW, Singleton AB, Meschia JF, Rosand J. Failure to validate association between 12p13 variants and ischemic stroke. New England Journal of Medicine 2010;362:1547-1550.

Houlihan LM, Davies G, Tenesa A, Harris S, Luciano M, Gow A, McGhee K, Liewald D, Porteous D, Starr J, Lowe G, Visscher P, Deary IJ. Common variants of large effect in F12, KNG1 and HRG are associated with activated partial thromboplastin time. American Journal of Human Genetics 2010;86:626-631.

Staff RT, Murray AD, Ahearn T, Salarirad S, Mowat DM, Starr JM, Deary IJ, Lemmon H, Whalley LJ. Brain volume and survival from age 78 to 85 years: the contribution of Alzheimer-type MRI findings. Journal of the American Geriatrics Society 2010;58:688-695.

Dykiert D, Hall D, van Gemeren N, Benson R, Der G, Starr JM, Deary IJ. The effects of high altitude on choice reaction time mean and intra-individual variability: Results of the Edinburgh Altitude Research Expedition 2008. Neuropsychology 2010;24:391-401.

Gale CR, Allerhand M, Sayer AA, Cooper C, Dennison EM, Starr JM, Ben-Shlomo Y, Gallacher JE, Kuh D, Deary IJ. The structure of the Hospital Anxiety and Depression Scale in Four Cohorts of Community-based Healthy Older People:  the HALCyon Programme. International Psychogeriatrics 2010;22:559-571.

Houlihan LM, Wyatt ND, Harris SE, Hayward C, Gow AJ, Marioni RE, Strachan MWJ, Price JF, Starr JM, Wright AF, Deary IJ. Variation in the uric acid transporter gene (SLC2A9) and memory performance. Human Molecular Genetics 2010;19:2321-2330.

Houlihan LM, Harris SE, Deary IJ, Starr JM. Replication association analysis of S100B and cognitive ageing. Psychiatric Genetics 2010;20:133-134.

Penke L, Munoz Maniega S, Murray C, Gow AJ, Valdes Hernandez MC, Clayden JD, Starr JM, Wardlaw JM, Bastin ME, Deary IJ. A general factor of brain white matter integrity predicts information processing speed in healthy older people. Journal of Neuroscience 2010;30:7569-7574.

McIlhagger R, Gow AJ, Brett CE, Corley J, Taylor M, Deary IJ, Starr JM. Differences in the haematological profile of healthy 70 year old men and women: normal ranges with confirmatory factor analysis. BMC Blood Disorders 2010;10:4.

Haggarty P, Hoad G, Harris SE, Starr JM, Fox HC, Deary IJ, Whalley LJ. Human intelligence and polymorphisms in the DNA methyltransferease genes involved in epigenetic marking. PLoS One 2010;5:e11329.

Luciano M, Houlihan LM, Harris SE, Gow AJ, Starr JM, Deary IJ. Association of existing and new candidate genes for anxiety, depression and personality traits in older people. Behavior Genetics 2010;40:518-532.

Johnson W, Gow AJ, Corley J, Starr JM, Deary IJ. Location in cognitive and residential space at age 70 reflects a lifelong trait over parental and environmental circumstances: The Lothian Birth Cohort 1936. Intelligence 2010;38:402-411.

Shenkin SD, Bastin ME, MacGillivray TJ, Eadie E, Deary IJ, Starr JM, Wardlaw JM. Carotid intima media thickness and cerebrovascular disease in community-dwelling older people without stroke. Stroke 2010;41:2083-2086.

Fieo R, Watson R, Deary IJ, Starr JM. A Revised ADL/IADL Instrument increases interpretive power: theoretical application for functional tasks exercise. Gerontology 2010;56:483-490.

Patterson M, Lonie JA, Starr JM. Thyroid function, cognition, functional independence and behavioural and psychological symptoms of dementia in Alzheimer’s disease. International Journal of Geriatric Psychiatry 2010;25:1196-1199.

Starr JM, Deary IJ. Renal function in a narrow-age cohort of adults at age 79 and 87 years. Age & Ageing 2010;39:750-752.

Corley J, Gow AJ, Starr JM, Deary IJ. Is body mass index in old age related to cognitive abilities? Psychology and Aging 2010;25:867-875.

Lopez LM, Mullen W, Zürbig P, Harris SE, Gow AJ, Starr JM, Porteous DJ, Mischak H, Deary IJ. A pilot study of urinary peptides as biomarkers for intelligence in old age. Intelligence 2011;39:46-53.

Murray C, Brett CE, Starr JM, Deary IJ. Which aspects of subjectively-reported quality of life are important in predicting mortality beyond known risk factors? The Lothian Birth Cohort 1921 study. Quality of Life Research 2011;20:81-90.

Birnie K, Cooper R, Martin RM, Kuh D, Aihie Sayer A, Alvarado BE, Bayer A, Christensen K, Cho S, Cooper C, Corley J, Craig L, Deary IJ, Demakakos P, Ebrahim S, Gallacher J, Gow AJ, Gunnell D, Haas S, Hemmingsson T, Inskip H, Jang S, Noronha K, Osler M, Palloni A, Rasmussen F, Santos-Eggimann B, Spagnoli J, Starr J, Steptoe A, Syddall H, Tynelius P, Weir D, Whalley LJ, Zunzunegui MV, Ben-Shlomo Y, Hardy R on behalf of the HALCyon study team ‘Childhood socioeconomic position and objectively measured physical capability levels in adulthood: a systematic review and meta-analysis’ PLoS ONE 2011;6:e15564.

Johnson W, Corley J, Starr JM, Deary IJ. Psychological and Physical Health at Age 70 in the Lothian Birth Cohort 1936: Links with Early Life IQ, SES, and Current Cognitive Function and Neighborhood Environment. Health Psychology 2011;30:1-11.

Rizzi TS, Vasquez AA, Rommelse N , Kuntsi J, Anney R, Asherson P, Buitelaar J, Banaschewski T, Ebstein R, Ruano D, Sophie Sluis S, Markunas CA, Ashley-Koch AE, Kollins SH, Anastopoulos AD, Hansell NK, Wright MJ , Montgomery GW, Martin NG, Harris SE, Davies G, Tenesa A, Porteous DJ, Starr JM, Deary IJ, Glaser B, Davey Smith G, Timpson NJ, Evans DM, Gill M, Miranda A, Mulas F, Oades RD, Roeyers H, Rothenberger A, Sergeant J, Sonuga-Barke E, Steinhausen HC, Taylor E, Faraone SV, Franke B, Posthuma D. The ATXN1 and TRIM31 genes are related to intelligence in an ADHD background: Evidence from a large collaborative study totaling 4963 subjects. Neuropsychiatric Genetics 2011;156:145-157.

Luciano M, Hansell NK, Lahti J, Davies G, Medland SE, Räikkönen K, Tenesa A, Widen E, McGhee KA, Palotie A, Liewald D, Porteous DJ, Starr JM, Montgomery GW, Martin NG, Eriksson JG, Wright MJ, Deary IJ. Whole genome association scan for genetic polymorphisms influencing information processing speed. Biological Psychology 2011;86:193-202.

Gow AJ, Johnson W, Pattie A, Brett CE, Roberts B, Starr JM, Deary IJ. Stability and change in intelligence from age 11 to ages 70, 79 and 87: the Lothian Birth Cohorts of 1921 and 1936. Psychology and Aging 2011;26:232-240.

Corley J, Jia X, Kyle JAM, Gow AJ, Brett CE, Starr JM, McNeill G, Deary IJ. Alcohol intake and cognitive function: the influence of childhood IQ and SES. Neuropsychology 2011;25:166-175.

Starr JM, Deary IJ. Blood pressure, socio-economic status and health in the Lothian 1921 Birth Cohort: a longitudinal study. Public Health 2011;125:196-200.

Henderson RD, Allerhand M, Patton N, Pattie A, Gow AJ, Dhillon B, Starr JM, Deary IJ. Vision and intelligence at age 83 in the Lothian Birth Cohort 1921. Intelligence 2011;39:148-154.

McNeill G, Jia X, Whalley LJ, Fox HC, Corley J, Gow AJ, Brett C, Starr JM, Deary IJ. Antioxidant and B vitamin intake in relation to cognitive function in later life in the Lothian Birth Cohort 1936. European Journal of Clinical Nutrition 2011;65:619-626.

Smith NL, Huffman JE, Strachan DP, Huang J, Dehghan A, Trompet S, Lopez LM, Shin SY, Baumert J, Vitart V, Bis JC, Wild SH, Rumley A, Yang Q, Uitterlinden AG, Stott DJ, Davies G, Carter AM, Thorand B, Polasek O, McKnight B, Campbell H, Rudnicka AR, Chen MH, Buckley BM, Harris SE, Peters A, Pulanic D, Lumley T, de Craen AJ, Liewald DC, Gieger C, Campbell S, Ford I. Gow AJ, Luciano M, Porteous DJ, Guo X, Sattar N, Tenesa A, Cushman M, Slagboom PE, Visscher PM, Spector TD, Illig T, Rudan I, Bovill EG, Wright AF, McArdle WL, Tofler G, Hofman A, Westendorp RG, Starr JM, Grant PJ, Karakas M, Hastie ND, Psaty BM, Wilson JF, Lowe GD, O'Donnell CJ, Witteman JC, Jukema JW, Deary IJ, Soranzo N, Koenig W, Hayward C. Genetic predictors of fibrin D-dimer levels in healthy adults. Circulation 2011;123:1864-1872.

Schiepers O, van Boxtel M, Harris S, Gow A, Pattie A, Brett C, de Groot R, Jolles J, Starr J, Deary I. MTHFR polymorphisms and cognitive ageing in the ninth decade: the Lothian Birth Cohort 1921. Genes, Brain and Behavior 2011;10:354-364.

Hope D, Bates T, Penke L, Gow AJ, Starr JM, Deary IJ. Fluctuating asymmetry and personality. Personality and Individual Differences 2011;50:49-52.

Frank RA. McRae AF. Pocklington AJ. van de Lagemaat LN. Navarro P. Croning MD. Komiyama NH. Bradley SJ. Challiss RA. Armstrong JD. Finn RD. Malloy MP. Maclean AW. Harris SE. Starr JM. Bhaskar SS. Howard EK. Hunt SE. Coffey AJ. Ranganath V. Deloukas P. Rogers J. Muir WJ. Deary IJ. Blackwood DH. Visscher PM. Grant SG. Clustered coding variants in the glutamate receptor complexes of individuals with schizophrenia and bipolar disorder. PLoS ONE 2011; 6:e19011.

Butchart C, Kyle J, McNeill G, Corley J, Gow AJ, Starr JM, Deary IJ. Flavonoid Intake in relation to cognitive function in later life in the Lothian Birth Cohort 1936. British Journal of Nutrition 2011;106:141-148.

Starr JM, Deary IJ. Sex differences in blood cell counts in the Lothian Birth Cohort 1921 between 79 and 87 years. Maturitas 2011;69:373-376.

Hamilton G, Harris SE, Davies G, Liewald DC, Tenesa A, Starr JM, Porteous D, Deary IJ. Alzheimer’s disease genes are associated with measures of cognitive ageing in the Lothian Birth Cohorts of 1921 and 1936. International Journal of Alzheimer's Disease 2011;505984.

Whalley LJ, Murray AD, Staff RT, Starr JM, Deary IJ, Fox HC, Lemmon H, Duthie SJ, Collins AR, Crawford JR. How the 1932 and 1947 mental surveys of Aberdeen schoolchildren provide a framework to explore the childhood origins of late onset disease and disability. Maturitas 2011;69:365-372.

Allerhand M, Ooi ET, Starr RJ, Alcorn M, Penke L, Drost E, MacNee W, Deary IJ, Starr JM. Skin ageing and oxidative stress in a narrow-age cohort of older adults. European Geriatric Medicine 2011;2:140-144.

Alfred T, Ben-Shlomo Y, Cooper R, Hardy R, Cooper C, Deary IJ, Elliott J, Gunnell D, Harris SE, Kivimaki M, Kumari M, Martin RM, Power C, Sayer AA, Starr JM, Kuh D, Day INM, and the HALCyon study team. Absence of association of a SNP in the TERT-CLPTM1L locus with age-related phenotypes in a large multi-cohort study: the HALCyon program. Aging Cell 2011;10:520-532.

Fieo RA, Austin EJ, Starr JM, Deary IJ. Calibrating ADL-IADL scales to improve measurement accuracy and to extend the disability construct into the preclinical range: a systematic review. BMC Geriatrics 2011;11:42.

Wain LV, Verwoert GC, O'Reilly PF, Shi G, Johnson T, Johnson AD, Bochud M, Rice KM, Henneman P, Smith AV, Ehret GB, Amin N, Larson MG, Mooser V, Hadley D, Dörr M, Bis JC, Aspelund T, Esko T, Janssens ACJW, Zhao JH, Heath S, Laan M, Fu J, Pistis G, Luan J, Arora P, Lucas G, Pirastu N, Pichler I, Jackson AU, Webster RJ, Zhang F, Peden JF, Schmidt H, Tanaka T, Campbell H, Igl W, Milaneschi Y, Hottenga J-J, Vitart V, Chasman DI, Trompet S, Bragg-Gresham JL, Alizadeh BZ, Chambers JC, Guo X, Lehtimäki T, Kühnel B, Lopez LM, Polašek O, Boban M, Nelson CP, Morrison AC, Pihur V, Ganesh SK, Hofman A, Kundu S, Mattace Raso FUS, Rivadeneira F, Sijbrands EJG, Uitterlinden AG, Hwang S-J, Vasan RS, Wang TJ, Bergmann S, Vollenweider P, Waeber G, Laitinen J, Pouta A, Zitting P, McArdle WL, Kroemer HK, Völker U, Völzke H, Glazer NL, Taylor KK, Harris TB, Alavere H, Haller T, Keis A, Tammesoo M-L, Aulchenko Y, Barroso I, Khaw K-T, Galan P, Hercberg S, Lathrop M, Eyheramendy S, Org E, Sõber S, Lu X, Nolte IM, Penninx BW, Corre T, Masciullo C, Sala C, Groop L, Voight BF, Melander M, O'Donnell CJ, Salomaa V, d'Adamo AP, Fabretto A, Faletra F, Ulivi S, Del Greco F, Facheris M, Collins FS, Bergman RN, Beilby JP, Hung J, Musk AW, Mangino M, Shin S-Y, Soranzo N, Watkins H, Goel A, Hamsten A, Gider P, Loitfelder M, Zeginigg M, Hernandez D, Najjar SS, Navarro P, Wild SH, Corsi AM, Singleton A, de Geus EJC, Willemsen G, Parker AN, Rose LM, Buckley B, Stott D, Orru M, Uda M, LifeLines Cohort Study, van der Klauw MM, Zhang W, Li X, Scott J, Ida Chen Y-D I, Burke GL, Kähönen M, Viikari J, Döring A, Meitinger T, Davies G, Starr JM, Emilsson V, Plump A, Lindeman JH, Hoen PAC’t, König IR, EchoGen consortium, Felix JF, Clarke R, C Hopewell JC, Ongen H, Breteler M, Debette S, DeStefano A, Fornage M, AortaGen Consortium, Mitchell GF, CHARGE Consortium Heart Failure Working Group Smith NL, KidneyGen consortium, Holm H, Stefansson K, Thorleifsson G, Thorsteinsdottir U, CKDGen consortium, Cardiogenics consortium, CardioGram, Samani NJ, Preuss M, Rudan I, Hayward C, Deary IJ, Wichmann H-E, Raitakari OT, Palmas W, Kooner JS, Stolk RP, Jukema JW, Wright AF, Boomsma DI, Bandinelli S, Gyllensten UB, Wilson JF, Ferrucci L, Schmidt R, Farrall M, Spector TD, Palmer LJ, Tuomilehto J, Pfeufer A, Gasparini P, Siscovick D, Altshuler D, Loos RJF, Toniolo D, Snieder H, Gieger C, Meneton P, Wareham NJ, Oostra BA, Metspalu A, Launer L, Rettig R, Strachan DP, Beckmann JS, Witteman JCM, Erdmann J, van Dijk KW, Boerwinkle E, Boehnke M, Ridker PM, Jarvelin M-R, Chakravarti A, Abecasis GR, Gudnason V, Newton-Cheh C, Levy D, Munroe PB, Psaty BM, Caulfield MJ, Rao DC, Tobin MD, Elliott P, van Duijn CM. Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure. Nature Genetics 2011;43:1005-1011.

Davies G, Tenesa A, Payton A, Yang J, Harris SE, Liewald D, Ke X, Le Hellard S, Christoforou A, Luciano M, McGhee K, Lopez L, Gow AJ, Corley J, Redmond P, Fox HC, Haggarty P, Whalley LJ, McNeill G, Goddard ME, Espeseth T, Lundervold AJ, Reinvang I, Pickles A, Steen VM, Ollier W, Porteous DJ, Horan M, Starr JM, Pendleton N, Visscher PM, Deary IJ. Genome-wide association studies establish that human intelligence is highly heritable and polygenic. Molecular Psychiatry 2011;16:996-1005.

Gale CR, Sayer AA, Cooper C, Dennison EM, Starr JM, Whalley LJ, Gallacher JE, Ben-Shlomo Y, Ku D, Hardy R, Craig L, Deary IJ, and the HALCyon Study Team. Factors Associated with Symptoms of Anxiety and Depression in Five Cohorts of Community-based Older People:  the HALCyon Programme. Psychological Medicine 2011;41:2057-2073.

Deary IJ, Johnson W, Gow AJ, Pattie A, Brett CE, Bates TC, Starr JM. Losing One’s Grip: A Bivariate Growth Curve Model of Grip Strength and Non-verbal Reasoning from Age 79 to 87 Years in the Lothian Birth Cohort 1921. Journal of Gerontology: Psychological Sciences 2011;66:699-707.

Sokunbi MO, Staff RT, Waiter GD, Ahearn TS, Fox HC, Deary IJ, Starr JM, Whalley LJ, Murray AD. Inter-individual differences in fMRI entropy measurements in old age. IEEE Transactions on Biomedical Engineering 2011;58:3206-3214.

Starr JM, Deary IJ. Socio-economic position predicts grip strength and its decline between 79 and 87 years: the Lothian Birth Cohort 1921. Age & Ageing 2011;40:749-752.

Artigas MS, Loth DW, Wain LV, Gharib SA, Obeidat M, Tang W, Zhai G, Zhao JH, Smith AV, Huffman JE, Albrecht E, Jackson CM, Evans DM, Cadby G, Fornage M, Manichaikul A, Lopez LM, Johnson T, Aldrich MC, Aspelund T, Barroso I, Campbell H, Cassano PA , Couper DJ, Eiriksdottir G, Franceschini N, Garcia M, Gieger C, Gislason GK, Grkovic I, Hammond CJ, Hancock  DB, Harris TB, Ramasamy A, Heckbert SR, Heliövaara M, Homuth G, Hysi PG, James AL, Jankovic S, Joubert  BR, Karrasch S, Klopp N, Koch B, Kritchevsky SB, Launer LJ, Liu Y, Loehr LR, t Lohman K, Loos RJF, Lumley T, Al Balushi KA, Ang WK, Barr RG, Beilby J, Blakey JD, Boban M, a Boraska V, Brisman J, Britton JR, Brusselle GG, Cooper C, Curjuric I, Dahgam S, Deary IJ, Ebrahim S, Eijgelsheim M, Francks  C, Gaysina D, Granell R, Gu X, Hankinson JL, Hardy R, Harris SE, Henderson J, Henry A, Hingorani AD, Hofman A, Holt PG, Hui J, Hunter ML, Imboden M, Jameson KA, Kerr SM, Kolcic I, Kronenberg F, Liu JZ, Marchini J, McKeever T, Morris AD, Olin A-C, Porteous D, Postma DS, Rich SS, Ring SM, Rivadeneira F, Rochat T, Sayer AA, Sayers I, Sly PD, Smith GD, Sood A, Starr JM, Uitterlinden AG, Vonk JM, Wannamethee SG, Whincup PH, Wijmenga C, Williams OD, Wong A, Mangino M, Marciante KD, McArdle WL, Meibohm B, Morrison AC, North KE, Omenaas E, Palmer LJ, Pietiläinen KH, Pin I, Polašek O, Pouta A, Psaty BM, Hartikainen A-L, Rantanen T, Ripatti S, I Rotter JI, Rudan I, Rudnicka AR, Schulz H, Shin S-Y, Spector TD, Surakka I, Vitart V, Völzke H, Wareham NJ, Warrington NM, Wichmann H-E, Wild SH, Wilk JB, Wjst M, Wright AF, Zgaga L, Zemunik T, Pennell CE, Nyberg F, Kuh D, Holloway JW, Boezen HM, Lawlor DA, Morris RW, Probst-Hensch N, The International Lung Cancer Consortium, GIANT consortium, Kaprio J, Wilson JF, Hayward C, Kähönen M, Heinrich J, Musk AW, Jarvis DL, Gläser S, Järvelin M-R, Stricker BH, Elliott P, O'Connor GT, Strachan DP, London SJ, Hall IP, Gudnason V, Tobin MD. Genome-wide association and large scale follow-up identifies 16 new loci influencing lung function. Nature Genetics 2011;43:1082-1090.

Brown LJE, Fordyce C, Zaghdani H, Starr JM, MacLullich AMJ. Detecting deficits of sustained visual attention in delirium. Journal of Neurology, Neurosurgery, and Psychiatry 2011;82:1334-1340.

Russ TC, Hamer M, Stamatakis E, Starr JM, Batty GD. Psychological Distress as a Risk Factor for Dementia Death. Archives of Internal Medicine 2011;171:1858-1859.

Wardlaw JM, Bastin ME, Valdes Hernandez M, Munoz Maniega S, Royle NA, Morris Z, Clayden JD, Sandeman EM, Eadie E, Murray C, Starr JM, Deary IJ. Brain Ageing, Cognition in Youth and Old Age, and Vascular Disease in the Lothian Birth Cohort 1936: Rationale, Design and Methodology of the Imaging Protocol. International Journal of Stroke 2011;6:547-559.

Cooper R, Hardy R, Aihie Sayer A, Ben-Shlomo Y, Birnie K, Cooper C, Craig L, Deary IJ, Demakakos P, Gallacher J, McNeill, Martin RM, Starr JM, Steptoe A, Kuh D on behalf of the HALCyon study team. Age and gender differences in physical capability levels from mid-life onwards: the harmonisation and meta-analysis of data from eight UK cohort studies. PLoS ONE 2011;6:e27899.

Gieger C, Radhakrishnan A, Cvejic A,  Tang W, Porcu E, Pistis G, Serbanovic‐Canic J, Elling U, Goodall AH, Labrune Y, Lopez LM, Mägi R, Meacham M, Okada Y, Pirastu N, Sorice R, Teumer A, Voss K, Zhang W, Ramirez‐Solis R, Bis JC, Ellinghaus D, Gögele M, Hottenga J-J, Langenberg C, Kovacs P, O'Reilly PF, Shin S-Y, Esko T, Hartiala J, Kanoni S, Murgia F, Parsa A, Stephens J, van der Harst P, van der Schoot CE, Allayee H, Attwood A, Balkau B, Bastardot F, Basu S, Baumeister SE, Biino G, Bomba L, Bonnefond A, Cambien F, Chambers JC, Cucca F, D'Adamo P, Davies G, de Boer RA, de Geus EJC, Döring A, Elliott P, Erdmann J, Evans DM, Falchi M, Feng W, Folsom AR, Frazer IH, Gibson QD, Glazer NL, Hammond C, Hartikainen A-L, Heckbert SR, Hengstenberg C, Hersch M, Illig T, Loos RJF, Jolley J, Khaw KT, Kühnel B, Kyrtsonis M-C, Lagou V, Lloyd‐Jones H, Lumley T, Mangino M, Maschio A, Mateo Leach I, McKnight B, Memari Y, Mitchell B, Montgomery GW, Nakamura Y, Nauck M, Navis G, Nöthlings U, Nolte IM, Porteous D, Pouta A, Pramstaller PP, Pullat J, Ring SM, Rotter JI, Ruggiero D, Ruokonen A, Sala C, Samani NJ, Sambrook J, Schlessinger D, Schreiber S, Schunkert H, Scott J, Smith NL, Snieder H, Starr JM, Stumvoll M, Takahashi A, Tang WHW, Taylor K, Tenesa A, Thein SL, Tönjes A, Uda M, Ulivi S, van Veldhuisen DJ, Visscher PM, Völker U, Wichmann H-E, Wiggins KL, Willemsen G, Yang T-P, Zhao JH, Zitting P, Bradley JR, Dedoussis GV, Gasparini P, Hazen SL, Metspalu A, Pirastu M, Shuldiner AR, van Pelt LJ, Zwaginga J-J, Boomsma DI, Deary IJ, Franke A, Froguel P, Ganesh SK, Jarvelin M-R, Martin NG, Meisinger C, Psaty BM, Spector TD, Wareham NJ, Akkerman J-WN, Ciullo M, Deloukas P, Greinacher A, Jupe S, Kamatani N, Khadake J, Kooner JS, Penninger J, Prokopenko I, Stemple D, Toniolo D, Wernisch L, Sanna S, Hicks AA, Rendon A, Ferreira MA, Ouwehand WH, Soranzo N. Sixty-eight genetic loci uncover new gene functions in megakaryopoiesis and platelet formation. Nature 2011;480:201-208.

MacLullich AMJ, Ferguson KJ, Reid LM, Deary IJ, Starr JM, Wardlaw JM, Walker BR, Andrew R, Seckl JR. 11ß-Hydroxysteroid dehydrogenase type 1, brain atrophy and cognitive decline. Neurobiology of Aging 2012;33:e1-e8.

Penke L, Valdés Hernandéz MC, Munoz Maniega S, Gow AJ, Murray C, Starr JM, Bastin ME, Deary IJ, Wardlaw JM. Brain iron deposits are associated with general cognitive ability and cognitive aging. Neurobiology of Aging 2012;33:510-517.

Luciano M, Lopez LM, Harris SE, Davies G, Starr JM, Deary IJ. Longevity candidate genes and their association with personality traits in the elderly. Neuropsychiatric Genetics 2012;159B:192-200.

Deary IJ, Yang J, Davies G, Harris SE, Tenesa A, Liewald D, Luciano M, Lopez LL, Gow AJ, Corley J, Redmond P, Fox HC, Rowe SJ, Haggarty P, McNeill G, Goddard ME, Porteous DJ, Whalley LJ, Starr JM, Visscher PM. Genetic contributions to stability and change in intelligence from childhood to old age. Nature 2012;482:212-215.
Gerrish A, Russo G, Richards A, Moskvina V, Ivanov D, Harold D, Sims R, Abraham R, Hollingworth P, Chapman J, Hamshere M, Pahwa JS, Dowzell K, Williams A, Jones N, Thomas C, Stretton A, Morgan AR, Lovestone S, Powell J, Proitsi P, Lupton MK, Brayne C, Rubinsztein DC, Gill M, Lawlor B, Lynch A, Morgan K, Brown KS, Passmore PA, Craig D, McGuinness B, Todd S, Johnston JA, Holmes C, Mann D, Smith AD, Love S, Kehoe PG, Hardy J, Mead S, Fox N, Rossor M, Collinge J, Maier W, Jessen F, Kölsch H, Heun R , Schürmann B,  van den Bussche H, Heuser I, Kornhuber J, Wiltfang J, Dichgans M, Frölich L, Hampel H, Hüll M, Rujescu D, Goate AM, Kauwe JSK, Cruchaga C, Nowotny P, Morris JC, Mayo K, Livingston G, Bass NJ, Gurling H, McQuillin A, Gwilliam R, Deloukas P, Davies G, Harris SE, Starr JM, Deary IJ,  Al-Chalabi A, Shaw CE, Tsolaki M, Singleton AB, Guerreiro R, Mühleisen TW, Nöthen MM, Moebus S, Jöckel K-H, Klopp N, Wichmann H-E, Carrasquillo MM, Pankratz VS, Younkin SG, Jones L, Holmans PA, O’Donovan MC, Owen MJ, Williams J. The role of variation at APP, PSEN1, PSEN2 and MAPT in late onset Alzheimer’s disease. Journal of Alzheimer’s Disease 2012;28:377-387.
Alfred T, Ben-Shlomo Y, Cooper R, Hardy R, Cooper C, Deary IJ, Gaunt TR, Gunnell D, Harris SE, Kumari M, Martin RM, Aihie Sayer A, Starr JM, Kuh D, Day INM, the HALCyon study team. A multi-cohort study of polymorphisms in the GH/IGF axis and physical capability: the HALCyon programme. PLoS ONE 2012;7:e29883.

Schiepers OJG, Harris SE, Gow AJ, Pattie A, Brett CE, Starr JM, Deary IJ. APOE E4 status predicts age-related cognitive decline in the ninth decade: longitudinal follow-up of the Lothian Birth Cohort 1921. Molecular Psychiatry 2012;17:315-324.

Lopez LM, Harris SE, Luciano M, Liewald D, Davies G, Gow AJ, Tenesa A, Payton A, Ke X, Whalley LJ, Fox H, McNeill G, Ollier W, Pickles A, Porteous DJ, Visscher PM, Horan MA, Pendleton N, Starr JM, Deary IJ. Evolutionary conserved longevity genes and human cognitive abilities in elderly cohorts. European Journal of Human Genetics 2012;20:341-347.

Murray AD, Staff RT, McNeil CJ, Salarirad S, Starr JM, Deary IJ, Whalley LJ. Brain lesions, hypertension and cognitive ageing in the 1921 and the 1936 Aberdeen birth cohorts. Age 2012;34:451-459.
Stolk L, Perry JRB, Chasman DI, He C, Mangino M, Sulem P, Barbalic M, Broer L, Byrne EM, Ernst F, Esko T, Franceschini N, Gudbjartsson DF, Hottenga J-J, Kraft P, McArdle PF, Porcu E, Shin S-Y, Smith AV, van Wingerden S, Zhai G, Zhuang WV, Albrecht E, Alizadeh BZ, Aspelund T, Bandinelli S, Barac-Lauc L, Beckmann JS, Boban M, Boerwinkle E, Broekmans FJ, Burri A, Campbell H, Chanock SJ, Chen C, Cornelis MC, Corre T, Coviello AD, d'Adamo P, Davies G, de Faire U, de Geus EJC Deary IJ, Dedoussis GVZ, Deloukas P, Ebrahim S, Eiriksdottir G, Emilsson V, Eriksson JG, Fauser BCJM, Ferreli L, Ferrucci L, Fischer K, Folsom AR, Garcia ME, Gasparini P, Gieger C, Glazer N, Grobbee DE, Hall P, Haller T Hankinson SE, Hass M, Hayward C, Heath AC, Hofman A, Ingelsson E, Janssens ACJW,  Johnson J, Karasik D, Kardia SLR, Keyzer J, Kiel DP, Kolcic I, Kutalik Z, Lahti J, Lai S, Laisk T, Laven JSE, Lawlor DA, Liu J, Lopez LM, Louwers YV, Magnusson PKE, Marongiu M, Martin NG, Martinovic-Klaric I, Masciullo C, McKnight B, Medland SE, Melzer D, Mooser V, Navarro P, Newman AB, Nyholt DR, N. Onland-Moret C, Palotie A, Paré G, Parker AN, Pedersen NL, Peeters PHM, Pistis G, Plump AS, Polasek O, Pop VJM, Psaty BM, Räikkönen K, Rehnberg E, Rudan I, Sala C, Salumets A, Scuteri A, Singleton A, Smith JA, Snieder H, Soranzo N, Stacey SN, Starr JM, Stathopoulou MG, Stirrups K, Stolk R, Styrkarsdottir U, Sun YV, Tenesa A, Thorand B, Toniolo D, Tryggvadottir L, Tsui K, Ulivi S, Van Dam RM, van der Schouw YT, van Gils CC, van Nierop P, Vink JJM, Visscher PM, Voorhuis M, Waeber G, Wallaschofski H, Wichmann HE, Widen E, Wijnands-van Gent CJM, Willemsen G, Wilson JF, Wolffenbuttel BHR, Wright AF, Yerges-Armstrong LM, Zemunik T, Zgaga L, Zillikens MC, Zygmunt M, the LifeLines cohort study, Arnold AM, Boomsma DI, Buring JE, Crisponi L, Demerath EW, Gudnason V, B Harris TB, Hu FB, Hunter DJ, Launer LJ, Metspalu A, Montgomery GW, Oostra1 B, Ridker PM, Sanna S, Schlessinger D, Spector TD, Stefansson K, Streeten EA, Thorsteinsdottir U, Uda M, Uitterlinden AG, van Duijn CM, Völzke H, Murray A, Murabito JM, Visser JA, Lunetta KL. Meta-analyses identify 13 novel loci associated with age at menopause and highlights DNA repair and immune pathways. Nature Genetics 2012;44:260-268.
Gow AJ, Corley J, Starr JM, Deary IJ. Reverse causation in activity-cognitive ability associations: the Lothian Birth Cohort 1936. Psychology and Aging 2012;27:250-255.

Brett CE, Gow AJ, Corley J, Pattie A, Starr JM, Deary IJ. Psychosocial factors and health as determinants of quality of life in community-dwelling older adults. Quality of Life Research 2012;21:505-516.

Kilgour AHM, Subedi D, Gray CD, Deary IJ, Lawrie SM, Wardlaw JM, Starr JM. Design and validation of a novel method to measure cross-sectional area of neck muscles included during routine MR brain volume imaging. PLoS ONE 2012; 7:e34444.

Hope D. Bates T. Gow AJ. Starr JM. Deary IJ. Minor physical anomalies, intelligence, and cognitive decline. Experimental Aging Research 2012;38:265-278.

Whalley LJ, Sharma S, Fox HC, Murray AD, Staff RT, Duthie AC, Deary IJ, Starr JM. Anticholinergic drugs in late life: adverse effects on cognition but not on progress to dementia. Journal of Alzheimer’s Disease 2012;30:253-261.

Harris SE, Martin-Ruiz  C, von Zglinicki  T, Starr JM, Deary IJ. Telomere length and aging biomarkers in 70 year-olds: the Lothian Birth Cohort 1936. Neurobiology of Aging 2012;33:1486,e3-8.

Stein JL, Medland SE, Vasquez AA, Hibar DP, Senstad RE, Winkler AM, Toro R, Appel K, Bartecek R, Bergmann Ø, Bernard M,. Brown AA, Canon D, Chakravarty M, Christoforou A, Domin M, Grimm O, Hollinshead M, Holmes AJ, Homuth G, Hottenga J-J, Lopez LM, Hansell NK, Hwang KS, Kim S, Laje G, Lee PH, Liu X, Loth E, Lourdusamy A, Muñoz Maniega S, Mattingsdal M, Nho K, Nugent AC, O’Brien C, Papmeyer M, Pütz B, Rijpkema M, Risacher SL, Rose EJ, Shen L, Sprooten E, Strengman E, Teumer A, van Eijk K, van Erp TGM, van Tol M-J, Wittfeld K, Wolf C, Woudstra S, Aleman A, Alhusaini S, Almasy L, Binder EB, Brohawn D, Cantor RM, Carless MA, Corvin A, Czisch M, Curran JE, Davies G, Delanty N, Depondt C, Duggirala R, Dyer TD, Erk S, Fagerness J, Fox PT, Freimer NB, Gill M, Göring HHH, Höhn D, Hosten N, Johnson MP, Kasperaviciute D, Kent JW, Kochunov P, Lancaster JL,. Lawrie SM, Liewald DC, Mandl R, Matarin M, Mattheisen M, Meisenzahl E, Melle I,. Moses EK, Mühleisen TW, Nauck M, Nöthen MN, Olvera RL, Pike GB, Puls R, Reinvang I, Rentería ME, Rietschel M, Roffman J, Royle NA, Rujescu D, Savitz J, Schnack HG, Schnell K, Steen VM, Valdés Hernández MC , Van den Heuvel M, van der Wee NJ, Van Haren NEM, Veltman JA, Völzke H, Walter H, Agartz I, Boomsma DI, Cavalleri GL, Dale AM, Djurovic S, Drevets WC, Hagoort P, Hall J, Jack CR, Foroud TM, Le Hellard S, Macciardi F, Montgomery GW, Poline JB, Porteous DJ, Sisodiya SM, Starr JM, Sussmann J, Toga AW,Veltman DJ, Weiner MW, the Alzheimer’s Disease Neuroimaging Initiative, IMAGEN Consortium, Saguenay Youth Study Group, Bis JC, M. Ikram A , Smith AV, Tzourio C, Vernooij MW, Launer LJ, DeCarli C, Seshadri S, for the CHARGE Consortium, Andreassen OA, Apostolova LG , Bastin ME , Blangero J, Brunner HG, Buckner RL, Cichon S, Coppola G, de Zubicaray GI, Deary IJ, Donohoe G, de Geus EJC, Espeseth T, Fernández G, Glahn DC, Grabe HJ, Jenkinson M, Kahn RS, McDonald C, McIntosh AM, McMahon FJ, McMahon KL, Meyer-Lindenberg A, Morris DW, Müller-Myhsok B, Nichols TE, Ophoff RA, Paus T, Pausova Z, Penninx BW, Hulshoff Po HE, Potkin SG, Sämann PG, Saykin AJ, Schumann G, Smoller JW, Wardlaw JM, Wright MJ, Franke B, Martin NG, Thompson PM, for the Enhancing NeuroImaging Genetics through Meta-Analysis (ENIGMA) Consortium. Common genetic polymorphisms are associated with human hippocampal and intracranial volumes. Nature Genetics 2012;44:552-561.

Mõttus  R , Gale CR, Starr JM, Deary IJ. On the street where you live: Neighbourhood deprivation and quality of life among community-dwelling older people. Social Science & Medicine 2012;74:1368-1374.

Luciano M, MacLeod AK, Payton A, Davies G, Ke X, Tenesa A, Ollier W, Starr JM, Horan MA, Pendleton N, Thomson PA, Porteous DJ, Deary IJ. Effects of gene copy number variants on personality and mood in ageing cohorts. Personality and Individual Differences 2012;53:393-397.

Lopez LM, Bastin ME, Muñoz Maniega S, Penke L, Davies G, Christoforou A, Valdés Hernández MC, Royle NA, Tenesa A, Starr JM, Porteous DJ, Wardlaw JM, Deary IJ.  A genome-wide search for genetic influences and biological pathways related to the brain's white matter integrity. Neurobiology of Aging 2012;33:1847.e1-1847.e14.

Luciano M, Mõttus R, Starr JM, McNeill G, Jia X, Craig LCA, Deary IJ. Depressive symptoms and diet: their effects on prospective inflammation levels in the elderly. Brains, Behavior and Immunity 2012; 26: 717-720.

Russ TC, Batty GD, Starr JM. Cognitive and behavioural predictors of survival in Alzheimer disease: results from a sample of treated patients in a tertiary-referral memory clinic. International Journal of Geriatric Psychiatry 2012;27:844-853.

Hagger-Johnson G, Mõttus R, Craig LCA, Starr JM, Deary IJ. Pathways from childhood intelligence and socio-economic status to late-life cardiovascular disease risk. Health Psychology 2012; 31: 403-412.

Dykiert D, Bates TC, Gow AJ, Penke L, Starr JM, Deary IJ. Predicting mortality from human faces. Psychosomatic Medicine 2012;74:560566.

Corley J, Gow AJ, Starr JM, Deary IJ. Smoking, childhood IQ, and cognitive function in old age. Journal of Psychosomatic Research 2012;73:132-138.

Tang W, Schwienbacher C, Lopez LM, Ben-Shlomo Y, Oudot-Mellakh T, Johnson AD, Samani NJ, Basu S, Gögele M, Davies G, Lowe GD, Tregouet D-A, Tan, A, Pankow JS, Tenesa A, Levy D, Volpato CB, Rumley A, Gow AJ, Minelli C, Yarnell JW, Porteous DJ, Starr JM, Gallacher J, Boerwinkle E, Visscher PM, Pramstaller PP, Cushman M, Emilsson V, Plump AS, Matijevic N, Morange P-E, Deary IJ, Hicks AA, Folsom AR. Genetic Associations for Activated Partial Thromboplastin Time and Prothrombin Time, their Gene Expression Profiles, and Risk of Coronary Artery Disease. American Journal of Human Genetics 2012;91:152-162.

Luciano M, Huffman JE, Arias-Vásquez A, Vinkhuyzen AAE, Giegling I, Payton A, Davies G, Zgaga L, Jazing J, Ke X, Martin NG, Hartmann AM, Ollier W, Tenesa A, Hayward C3, Verhagen M, Montgomery GW, Konte B, Pickles A, Starr JM, Vitart V, Vos P, Madden PAF, Konnerth H, Horan MA, Porteous DJ, Campbell H, Vermeulen SH, Heath AC, Visscher P, Wright A, Polasek O, Franke B, Wilson JF, Wray N, Rujescu D, Buitelaar J, Pendleton N, Rudan I, Ian J Deary Genome-wide association uncovers shared genetic effects among personality traits and mood states. American Journal of Medical Genetics, Part B: Neuropsychiatric Genetics 2012;159B:684-695.

Shiue I, Starr JM. Circulating urine phthalates are not associated with cognition decline in adults and the elderly: NHANES, 1999-2002. Neuroepidemiology 2012;39:143-144.

Russ TC, Stamatakis E, Hamer M, Starr JM, Kivimäki M, GD Batty. Association between psychological distress and mortality: an individual participant pooled analysis of ten prospective cohort studies. BMJ 2012;345: e4933.

Dykiert D, Der G, Starr JM, Deary IJ. Sex differences in reaction time: mean and intra-individual variability across the life span. Developmental Psychology 2012;48:1262-1276.

Dunlop MG, Dobbins SE, Farrington SM, Jones AM, Palles C, Whiffin N, Tenesa A, Spain S, Broderick P, Ooi LY, Domingo E, Smillie C, Henrion M, Frampton M, Martin L, Grimes G, Gorman M, Semple C, Ma YP, Barclay E, Prendergast J, Cazier JB, Olver B, Penegar S, Lubbe S, Chander I, Carvajal-Carmona LG, Ballereau S, Lloyd A, Vijayakrishnan J, Zgaga L, Rudan I, Theodoratou E, Colorectal Tumour Gene Identification (CORGI) Consortium, Starr JM, Deary I, Kirac I, Kovacevic D, Aaltonen LA, Renkonen-Sinisalo L, Mecklin JP, Matsuda K, Nakamura Y, Okada Y, Gallinger S, Duggan DJ, Conti D, Newcomb P, Hopper J, Jenkins MA, Schumacher F, Casey G, Easton D, Shah M, Pharoah P, Lindblom A, Liu T, Swedish Low-Risk Colorectal Cancer Study Group, Smith CG, West H, Cheadle JP, COIN Collaborative Group, Midgley R, Kerr DJ, Campbell H, Tomlinson IP, Houlston RS. Common variation near CDKN1A, POLD3 and SHROOM2 influences colorectal cancer risk. Nature Genetics 2012;44:770-776.

Murray C, Pattie A, Starr JM, Deary IJ. Does cognitive ability predict mortality in the ninth decade? The Lothian Birth Cohort 1921. Intelligence 2012;40:490-498.

Russ TC, Batty GD, Hearnshaw GF, Fenton C, Starr JM. Geographical variation in dementia: systematic review with meta-analysis. International Journal of Epidemiology 2012;41:1012-1032.

Gale CR, Cooper R, Craig L, Elliott J, Kuh D, Richards M, Starr JM, Whalley LJ, Deary IJ. Cognitive Function in Childhood and Lifetime Cognitive Change in Relation to Mental Wellbeing in Four Cohorts of Older People. PLoS ONE 2012;7:e44860.

McQuillan R, Eklund N, Pirastu N, Kuningas M, McEvoy BP, Esko T, y Corre T, Davies G, Kaakinen M, Lyytikäinen L-P, Kristiansson K, Havulinna AS, Gögele M, Vitart V, Tenesa A, Aulchenko Y, Hayward C, Johansson Å, Boban M, Ulivi S, Robino A, Boraska V, Igl W, Wild SH, Zgaga L, Amin N, Theodoratou E, Polašek O, Girotto G, Lopez LM, Sala C, Lahti J, Laatikainen T, Prokopenko I, Kals M, Viikari J, Yang J, Pouta A, Estrada K, Hofman A, Freimer N, Martin NG, Kähönen M, Milani L, Heliövaara M, Vartiainen E, Räikkönen K, Masciullo C, Starr JM, Hicks AA, Esposito L, Kolčić I, Farrington SM, Oostra B, Zemunik T, Campbell H, Enroth S, Pehlic M, Faletra F, Porteous D, Pistis G, Widén E, Salomaa V, Koskinen S, Fischer K, Lehtimäki T, Heath A, McCarthy MI, Rivadeneira F, Montgomery GW, Tiemeier H, Hartikainen A-L, Madden PAF, d'Adamo P, Hastie ND, Gyllensten U, Wright AF, van Duijn CM, Dunlop M, Rudan I, Gasparini P, Pramstaller PP, Deary IJ, Toniolo D, Eriksson JG, Jula A, Raitakari OT, Metspalu A, Perola M, Järvelin M-J, Uitterlinden A, Visscher PM, Wilson JF. Evidence of inbreeding depression on human height. PLoS Genetics 2012;8 e1002655.

Penke L, Muñoz Maniega S, Bastin M, Valdés Hernandéz MC, Murray C, Royle NA, Starr JM, Wardlaw JM, Deary IJ.  Brain white matter tract integrity is associated with information processing speed and general intelligence. Molecular Psychiatry 2012;17:955.

Penke L, Muñoz Maniega S, Bastin M, Valdés Hernandéz MC, Murray C, Royle NA, Starr JM, Wardlaw JM, Deary IJ.  Brain white matter tract integrity as a neural foundation for general intelligence. Molecular Psychiatry 2012;17:1026-1030.

 

In press articles

Houlihan L, Harris SE, Luciano M, Starr JM, Visscher PM, Deary IJ. Candidate genes for cognitive impairments: do they influence mental ability and cognitive ageing in a normal population? American Journal of Medical Genetics (in press).

Alfred T, Ben-Shlomo Y, Cooper R, Hardy R, Cooper C, Deary IJ, Gunnell D, Harris SE, Kumari M, Martin RM, Moran CN, Pitsiladis YP, Ring SM, Sayer AA, Smith GD, Starr JM, Kuh D, Day INM, and the HALCyon study team. ACTN3 genotype, athletic status and lifecourse physical capability: meta-analysis of the published literature and findings from nine studies. Human Mutation (in press).

Hope D, Bates T, Penke L, Gow AJ, Starr JM, Deary IJ. Symmetry of the face in old age reflects childhood social status. Economics and Human Biology (in press).

Mõttus R, McNeill G, Jia X, Craig LCA, Starr JM, Deary IJ. The associations between personality, diet and body mass index in older people. Health Psychology (in press).

Law E, Starr JM, Connelly PJ. Dementia research - what do different public groups want? A survey by the Scottish Dementia Clinical Research Network. Dementia: the international journal of social research and practice (in press).

Deary IJ, Gow AJ, Pattie A, Starr JM. Cohort Profile: The Lothian Birth Cohorts of 1921 and 1936. International Journal of Epidemiology (in press).

Mõttus  R, Starr JM, Deary IJ. Predicting tooth loss in older age: Interplay between personality and socioeconomic status. Health Psychology (in press).

Whalley LJ, Staff RT, Murray AD, Deary IJ, Starr JM. Genetic and environmental factors in late onset dementia: possible role for early parental death. International Journal of Geriatric Psychiatry (in press).

Mottus R, Johnson W, Starr JM, Deary IJ. Correlates of personality trait levels and their changes in very old age: The Lothian Birth Cohort 1921. Journal of Research in Personality (in press).

Law E, Connelly PJ, Randall E, McNeill C, Fox HC, Parra MA, Hudson J, Whyte L-A, Johnstone J, Gray S, Starr JM.  Does the Addenbrooke’s Cognitive Examination-Revised add to the Mini-Mental State Examination in established Alzheimer disease? Results from a national dementia research register. International Journal of Geriatric Psychiatry (in press).

Hamilton G, Harris SE, Davies G, Liewald DC, Tenesa A, Payton A, Horan MA, Ollier WER, Pendleton N, the Genetic and Environmental Risk for Alzheimer’s disease (GERAD1) consortium, Starr JM, Porteous D, Deary IJ. The role of ECE-1 variants in cognitive ability in old age and Alzheimer's disease risk. Neuropsychiatric Genetics (in press).

Grinton ME, Laude A, MacGillivray T, Henderson R, Starr JM, Deary IJ, Aspinall P, Dhillon B. The association between retinal vessel morphology and retinal nerve fiber layer thickness in an elderly population. Ophthalmic Surgery, Lasers & Imaging (in press).

McIntosh AM, Bastin ME, Luciano M, Muñoz Maniega S, Valdés Hernández M, Royle NA, Hall J, Murray C, Lawrie SM, Starr JM, Wardlaw JM, Deary IJ. Neuroticism, depressive symptoms and white matter integrity in the Lothian Birth Cohort 1936. Psychological Medicine (in press).

Gow AJ, Bastin ME, Muñoz Maniega S, Valdés Hernández M, Morris Z,  Murray C, Royle N, Starr JM, Deary IJ, Wardlaw JM. Neuroprotective lifestyles and the aging brain: activity, atrophy and white matter integrity. Neurology (in press).

Miller TD, Ferguson KJ, Reid LM, Wardlaw JM, Starr JM, Seckl JR, Deary IJ, MacLullich AMJ. Cerebellar vermis size and cognitive ability in community-dwelling elderly men. Cerebellum (in press).

Johnson W, Gow AJ, Corley J, Redmond P, Henderson R, Murray C, Starr J, Deary IJ. Can we spot deleterious ageing in two waves of data? The Lothian Birth Cohort 1936 from ages 70 to 73. Longitudinal and Life Course Studies (in press).

Mõttus  R , Johnson W, Murray C, Wolf MS, Starr JM, Deary IJ. Towards understanding the links between health literacy and physical health. Health Psychology (in press).

Dykiert D, Der G, Starr JM Deary IJ. Age Differences in Intra-Individual Variability in Simple and Choice Reaction Time: Systematic Review and Meta-Analysis. PloS ONE (in press).

van der Harst P, Zhang W, Leach IM, Rendon A, Verweij N, Sehmi J, Paul DS, Elling U, Allayee H, Li X, Radhakrishnan A, Tan S-T, Voss K, Weichenberger CX, Albers CA, Al-Hussani A, Asselbergs FW, Ciullo M, Danjou F, Dina C, Esko T, Evans DM, Franke L, Gibson QD, Gögele M, Hartiala J, Hersch M, Holm H, Hottenga J-J, Kanoni S, Kleber ME, Lagou V, Langenberg C, Lopez LM, Lyytikäinen L-P, Melander O, Murgia F, Nolte IM, O'Reilly PF, Pirastu N, Porcu E, Portas L, Prokopenko I, Ried JS, Shin S-Y, Tang CC, Teumer A, Traglia M, Ulivi S, Westra H-J, Yang J, Zhao JH, Anni F, Abdellaoui A, Attwood A, Balkau B, Bandinelli S, Bastardot F, Benyamin B, Boehm BO, Cookson WO, Das D, de Bakker PIW, de Boer RA, de Geus EJC, de Moor MH, Dimitriou M, Domingues FS, Döring A, Engström G, Eyjolfsson GI, Ferrucci L, Fischer K, Galanello R, Garner SF, Genser B, Girotto G, Gudbjartsson DF, Harris SE, Hartikainen A-L, Hedblad B, Illig T, Jolley J, Kähönen M, Kema IP, Kemp JP, Liang L, Lloyd-Jones H, Loos RJF, Meacham S, Medland SE, Meisinger C, Memari Y, Mihailov E, Miller K, Moffatt MF, Nauck M, Novatchkova M, Nutile T, Olafsson I, Onundarson PT, Parracciani D, Parsa A, Penninx BW, Perseu L, Piga A, Pistis G, Pouta A, Puc U, Raitakari O, Ring SM, Robino A, Ruggiero D, Ruokonen A, Saint-Pierre A, Sala C, Salumets A, Sambrook J, Schepers H, Schmidt CO, Silljé HHW, Sladek R, Smit JH, Starr JM, Stephens J, Sulem P, Tanaka T, Thorsteinsdottir U, Tragante V, van Gilst WH, van Pelt LJ, van Veldhuisen DJ, Völker U, Whitfield JB, Willemsen G, Winkelmann BR, Wirnsberger G, Lifelines Cohort Study, Algra A, Cucca F, d'Adamo AP, Danesh J, Deary IJ, Elliott P, Fortina P, Froguel P, Gasparini P, Greinacher A, Hazen SL, Jarvelin M-R, Khaw KT, Lehtimäki T, Maerz W, Martin NG, Metspalu A, Mitchell BD, Montgomery GW, Moore C, Navis G, Pirastu M, Pramstaller PP, Ramirez-Solis R, Schadt E, Scott J, Shuldiner AR, Smith GD, Smith JG, Snieder H, Sorice R, Spector TD, Stefansson K, Stumvoll M, Tang WHW, Toniolo D, Tönjes A, Visscher PM, Vollenweider P, Wareham NJ, Wolffenbuttel BHR, Boomsma DI, Beckmann JS, Dedoussis GV, Deloukas P, Ferreira MA, Sanna S, Uda M, Hicks AA, Penninger JM, Gieger C, Kooner JS, Ouwehand WH, Soranzo N, Chambers JC. 75 genetic loci influencing the human red blood cell. Nature (in press).

Mõttus R,  Luciano M, Starr JM, Pollard MC, Deary IJ. Personality traits and inflammation in individuals aged around 70 and 73 years. Psychosomatic Medicine (in press).

Ritchie SJ, Bates TC, Der G, Starr JM, Deary IJ. Education is associated with higher later-life IQ scores, but not with faster cognitive processing speed. Psychology and Aging (in press).

Zammit AR, Starr JM, Johnson W, Deary IJ. Profiles of Physical, Emotional and Psychosocial Wellbeing in the Lothian Birth Cohort 1936. BMC Geriatrics (in press).

Piccinin AM, Muniz G, Clouston S, Reynolds CA, Thorvaldsson V, Deary IJ, Deeg D, Johansson B, Mackinnon A, Spiro A, Starr JM, Skoog I, Hofer SM. Coordinated Analysis of Age, Sex, and Education Effects on Change in MMSE Scores. Journal of Gerontology: Psychological Sciences (in press).



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